How Does Cell Therapy Work?

The active ingredient of cell therapy is mesenchymal stem cells (MSC) which are adult multipotent stem cells that have the potential to:

Regenerate the degenerated cartilage and, in addition, prevent the formation of scar tissue.
Exert trophic, immunosuppressive, anti-inflammatory and anti-apoptotic effects and activate the body’s own stem/progenitor cells, modulating the local environment and thereby stimulating a local tissue repair.
Their ability to form cartilage, their low immunogenicity and known anti-inflammatory effects make adipose-derived stem cells an ideal candidate for cartilage repair.
Stem cell therapy for animal treatment

EquiCell And CaniCell Therapy Products

Medrego CaniCell and EquiCell products. Dog and Horse Stem Cell Therapy.

Medrego EquiCell and CaniCell are efficient stem cell therapy products that contain active mesenchymal stem cells (MSC).

One dose of therapy product usually has from 3 to 10 million unmodified sterile animal mesenchymal tissue cells.  For autologous treatment option, one dose can contain also 15, 20, 25 million cells per dose.

Stem cell count in one product dose do not directly correlate with the effect of the treatment. Stem cells will act as a signaling mechanism in the body and attract the body’s own cells for regeneration as well.

Medrego EquiCell and CaniCell therapies are not medicinal products** or veterinary drugs. Medrego EquiCell and CaniCell products contain unmodified sterile animal mesenchymal tissue cells only for transplantation in horses/dogs/cats/camels. The product is also made for a specific doctor’s order.

** Definition of a veterinary medicinal product in the European Union can be found in Article 2 of Directive 2004/28/EC, an amendment of Directive 2001/82/EC relating to veterinary medicinal products.

Use Cases For Stem Cell Therapy Products

Stem Cell Therapy can help in the tendon, ligament, joint, cartilage, and bone tissue injury treatment, decrease inflammation and pain, heal damaged cells, prevent their further deterioration, promote active tissue regeneration and improve animals’ overall health.

For Dogs

Arthritis and Osteoarthritis

Degenerative joint disease, hip dysplasia, calcifications, common degeneration, and inflammation.

Soft tissue injuries

Stem cell treatment for dog tendon and ligament injuries, cruciate injuries, tears, ruptures, inflammation.

Immunomodulation treatment

Intravenous stem cell treatment for better recovery after surgeries and injuries, as well as overall health improvement. This treatment can also help to boost energy level and preclude the signs of ageing.

Compassionate use

Includes such conditions as degenerative myelopathy, canine gingivitis, end-stage renal disease, liver and kidney failure, allergy, auto-immune, inflammatory bowel disease, pulmonary fibrosis, IMHA, atopy, and spine trauma.

For Horses

Tendon and ligament treatment

Stem cell treatment for soft tissue (tendon and ligament) injuries. The most popular use of stem cells for the horse industry.

Cartilage and joint repair

Stem cell treatment to treat symptoms and support the formation of normal hyaline cartilage, keeping horse healthier for longer.

Immunomodulation treatment

Intravenous (IV) stem cell treatment for better recovery after surgeries and injuries, as well as overall health improvement. This treatment can also help to boost energy level and preclude the signs of ageing.

Compassionate use

Includes such conditions as degenerative myelopathy, feline gingivitis, end-stage renal disease, liver and kidney failure, allergy, auto-immune, inflammatory bowel disease, pulmonary fibrosis, IMHA, atopy, and spine trauma.

Stem Cell Therapy Options


Allogeneic Stem Cell Therapy: How It Works?

In order to obtain allogenic stem cells for the treatment, there is no invasive procedure required for the injured animal. This product contains adipose tissue cells from another, young and healthy donor animal. It means the high-quality of the cells with maximum safety profile. In case of animals own stem cells, they are very much dependent on overall health and age of the animal, so in many cases, donor cells could be better performing.

A veterinarian can easily order Medrego Cell Therapy by phone, e-mail, order form or local partner and it will be delivered (on dry ice) to the clinic within 24-72 hours.

Stem Cell Therapy doses are frozen and they can be easily stored in clinic’s regular freezer (-20 C) for up to 6 months, or a professional freezer (-85 C) up to 1 year.

Please get in touch with us to learn more about the easy procedure protocol and start offering Stem Cell Therapy in your practice.

The benefit of Allogenic Stem Cell Therapy is in its ease of use, application speed and costs – the product can be delivered to veterinarian practice right after the order and kept in the freezer for the moment when you need it.

Medrego Infographic Animal Allogeneic Stem Cell Treatment How it works explainer Allogenic

Autologous Stem Cell Therapy: How It Works?

Autologous Stem Cell Therapy product is derived from the animal’s own (autologous) adipose tissue and provides the regenerative effect.

It takes about 2-4 weeks for the cells to be ready to use, and the efficiency of this treatment depends on the overall health of the individual animal – the patient. In most of the cases, cells work very well, but if the patient is older and body condition is not very good, cells might be less active.

In order to obtain autologous stem cells for therapy, the animal must be anesthetized, and surgical procedures must be performed by the treating veterinarian to extract cells needed for the therapy.

Medrego will provide the kit for the collection of adipose tissue, as well as further instructions about storing and sending the obtained cells.  

We can also store extra therapeutic doses of stem cells for future use as well as storing a retention sample for potential future culturing.

Autologous and Allogeneic Stem Cell Therapy can both be used for the same animal injuries and diseases mentioned above. The success rate of both treatments has been proven in many studies and use cases.

Medrego Infographic Animal Autologous Stem Cell Treatment How it works explainer Horse and Dog stem cell treatment

Safety Of Stem Cell Therapies

In order to ensure highly effective, safe and universal customized products for problems, starting from everyday injuries to custom immunomodulation treatments, we continuously are working alongside scientific rigor.

All the processes are exposed to expertise from our highly qualified scientists and experts who constantly are following the latest innovations, medicine tendencies and scientific researches to integrate most effective things into our projects.

Since 2003 there have been tens of thousands of animals who have experienced stem cell treatments with great success.
More than 250 scientific researches approve the safety of stem cell therapy. Both autologous and allogeneic.
Safety is our top priority: Certified quality assurance and quality control systems are in place.
We follow ISO 9001 protocols and the EMA Committee for Medicinal Products for Veterinary safety guidelines.
In the case of Allogeneic therapy, it is a non-invasive procedure to manufacture a mesenchymal cell product with decreased risks.
Stem cells aren’t substantially modified and maintain their original form and characters.
We provide independent testing of the donor (3rd party testing).
Each batch of cell product is also tested for sterility and endotoxin levels.

Conditions That Disqualify Pet For Stem Cell Therapy:

  • Cancer of undetermined type;
  • Tumor of undetermined type;
  • Active systemic (affecting the entire body) infection

 

Negative Outcomes Of Stem Cell Therapy:

It is rare for owners or veterinarians to report a negative reaction to Cell therapy. We research any such case and the likely cause for these was manipulation of the joint during the injection.

Most of these negative impacts resolved after several days.

Negative outcomes due to anesthesia risk is the same as with any surgical procedure.

Benefits Of Partnering With Medrego

Experienced manufacturer with more than 500+ successful injections delivered for both horses and dogs.
Very attractive partnership terms. Affiliate and referral programs.
No capital investment or equipment needed to start offering Stem Cell Therapy.
The professional management team and great partner support. More than 15-years experience in the biotechnology & life science industry. We consult European commission, KPMG and others on cell-based therapies.
High success rate (up to 90%) for our use cases and less repeated injuries.
First results of the therapy can be seen already after two weeks. Simple one injection treatment process, same-day treatment for your clients.
Personalized support from our team.
Well-known brand and marketing support. We are ready to invest and provide with full marketing support in your region to drive clients towards your veterinarian practice.
Ready-on-demand and Cost-effective product.

Colleagues’ Feedback About Medrego Stem Cell Therapy

FAQ

In case you have any uncertainty please go to our frequently asked questions section and find your answer. Besides, we are opened to hear from you if you can’t find the information you were looking for.

 

Science and publications

Our work is based on strong scientific research groundwork. So far there have been published more than 250 studies in the peer-reviewed scientific and professional medical literature. Visit our science and publications section and find out more about stem cells and the life science industry.

Related articles:

Autologous and allogeneic stem cell therapy for animal treatmentAutologous vs. Allogeneic – which one to choose?

Allogeneic (donor-derived) and autologous (own-derived) stem cell therapies – which one to choose and why?

Questions and answers about the stem cell therapy for animal treatmentAnimal Stem Cell Therapy: Questions & Answers

We gathered some frequently asked questions about animal stem cell therapy and provided some answers.

Horse tissue (tendon, ligament) treatment with stem cell therapyTissue healing & stem cells

If we know how horse tissue heals, we can also understand how exactly stem cell therapy helps with tissue healing.