Medrego horse tendon and ligament Injuries and 7 ways to treat them Sport Horses Regeneration Stem Cells Treatment or Therapy

As a horse propels himself toward a jump, he shifts his weight backward, gathers his hind end, and with a smooth propulsive motion extends his hind limbs, releasing amassed energy that launches his half-ton body into the air. He curls his fore and hind limbs toward his body, then transitions into landing by protracting his shock-absorbing forelimbs. This athletic move—among others—is a massive coordinated feat, straining the hind tendons during launch and the forelimb tendons and associated ligaments at landing and that is the way how horse tendon injury can emerge. 

It’s no wonder tendon and ligament injuries comprise up to 46% of sport horse injuries

says Nick Huggons, DVM, Dipl. ACVS, surgeon, and co-owner of San Luis Rey Equine Hospital, in Bonsall, California.

Superficial Digital Flexor Tendon Injury

Equine tendon and ligament injury treatment

Tendons are bands of dense connective tissue tying muscle to bone or cartilage. These structures are designed to passively transfer force across joints or provide movement. The horse’s digital flexor tendons have evolved to store energy, absorb shock, and support weight-bearing joints.

Researchers have reported SDFT injuries as the most common type of tendon/ligament injury. In one study of British racehorses and National Hunt horses, SDFT injuries accounted for up to 90% of tendon/ligament injuries.

A veterinarian’s best chance to make a definitive diagnosis on horse tendon injury is seven to 10 days following the injury.

This allows time for inflammation to subside and for the lesion(s) to become visible on ultrasound. Because this imaging modality allows the veterinarian to assess an injury’s chronicity and size, performing repeated exams during the rehab period can help guide rehabilitation and treatment protocols. Ultrasound is also the most sensitive indicator of impending reinjury from an overly aggressive exercise regimen.

“If left untreated, damage to a tendon can continue to increase in severity due to the inflammatory process.” – says dr. Alfredo Romero.


Deep Digital Flexor Tendon Injury

The deep digital flexor tendon (DDFT) arises from three locations in the upper forelimb: the humerus, radius, and ulna. It then courses down the carpal canal (the depression running down the back of the knee) and crosses over the navicular bone before inserting at the back of the coffin bone, lying deep beneath the SDFT and just over the suspensory ligament.

In the hind limb, the DDFT originates from two areas of the tibia and also inserts on the coffin bone. This tendon plays a role in the knee and forefoot flexion, forelimb elbow joint extension, and hock and hindfoot flexion and extension.

Horse tendon injury occurs most frequently within the hoof capsule and the sheath around the tendon, likely from repetitive excessive loading. Usually, lesions appear in the body or borders of the tendon at the fetlock joint level and are more common in the hind than forelimbs. The four most common DDFT lesions are tendon enlargements or changes in shape, focal core lesions, mineralizations, and marginal tears.

While veterinarians can diagnose the first three using ultrasound, they typically must use MRI (either standing or under general anesthesia) or tenoscopy (using a fibre-optic camera to explore the tendon under general anesthesia) to diagnose tears.

Equine suspensory desmitis treatment

Suspensory Desmitis

A ligament is a band of tough connective tissue joining two bones or cartilages. Suspensory ligaments (SL) originate from the back of the fore and hind cannon bones.

The SL’s main function is to prevent the fetlock joint from overextending. Researchers have shown that appropriate training in racehorses can improve the SL’s strength.

Although the suspensory ligament can fail at any point along its length, veterinarians commonly diagnose proximal (upper) suspensory desmitis (PSD) in performance horses’ limbs. It usually causes acute onset lameness that can resolve within 24 hours unless the horse continues to work hard. Lameness is typically mild to moderate, and veterinarians often detect it in Standardbreds trotting at high speeds.

Veterinarians diagnosing horses with hind-limb PSD often examine horses initially because of poor performance rather than overt lameness. Although hind-limb PSD occurs in horses of all ages and disciplines, it is especially common in high-level dressage horses. Romero notes conformational predispositions can include straight hocks and long toes/short heels.

Veterinarians use nerve blocks and ultrasonography to diagnose this injury. Prognosis for hind-limb PSD following conservative therapy alone is poor, with only 14% of horses resuming full work without lameness for more than a year. Specific PSD treatment includes corrective hoof trimming and applying specialty shoes such as egg bar shoes.

Horse Tendon Injury Symptoms

The weekend race is over and after a hard competition, your horse comes up to you with some mild swelling and heat in his lower foreleg.

You go home. After a few days, everything seems fine with the horse, so you think there is nothing wrong.

And then you forget all about it.

But should you really just forget it?

What if that mild swelling and heat in his lower foreleg was a clear-cut symptom of serious tendon injury?

Damage to horse tendon causes inflammation, heat, and swelling.

In case of severe damage, the limb becomes very painful and swollen, and the horse may become severely lame. If the tendon is ruptured, the horse may even walk with the toe tipped up.

Notice very carefully how your horse is walking.

If you think something is wrong with your horse, then don’t wait even for a second. The best way to diagnose tendon injury is by calling your veterinarian so he can take a look at it.

Horse Tendon Injury Recovery Time

As mentioned before – horse tendon injury is not a light matter. It needs to be treated the right way and with patience.

The mildest tendon injury recovery can take between 9-12 months. Yes, that’s a very long time, but if you want your horse to return to normal after an injury like that, then it is worth waiting.

A more severe tendon injury can take much longer to heal. Another thing to consider is how old the horse is – the older the horse, the longer it will take to heal from a serious injury.

But that does not mean that the horse will return to completely normal functioning as before. One of the reasons is that the fibres in a repaired tendon are less elastic, making them more prone to strains and tears than the collagen fibres of a normal, healthy tendon.

Traditional Treatments

If you suspect your horse has an acute tendon or ligament injury, work with your veterinarian and start therapies such as bandaging, anti-inflammatory administration, and stall rest immediately to minimize inflammation. Rest limits loading and further injury, but occasionally veterinarians might apply splints and casts to further immobilize severe injuries that have caused fetlock joint overextension.

Traditional horse treatment versus stem cell therapy

1. Anti-inflammatory drugs

Anti-inflammatory and analgesic (pain) drugs are essential for horse tendon injury treatment: Oral or intravenous (IV) phenylbutazone (Bute) supplies a potent analgesic effect; oral, IV, or intramuscular (IM) steroids provide a strong anti-inflammatory effect; and intramuscular polysulfated glycosaminoglycan (PSGAG) offers soft tissue anti-inflammatory effects.

2. Physical Therapy

Physical therapy should start with 15-minute sessions of knee and fetlock joint flexions within the horse’s range of motion. Your veterinarian should then prescribe a controlled exercise regimen based on the injury’s ultrasonographic appearance. Frequent rechecks and ultrasound exams should dictate each stepwise increase in exercise level.

Popular horse tendon injury treatment ways such as extracorporeal shock wave therapy (ESWT) and counterirritation (using chemical blistering or thermal “pin firing”) can be controversial. Scientists have shown no difference in collagen arrangement and scarring from pin firing and have concluded it is not an effective treatment. There are also conflicting views on ESWT, as researchers have demonstrated in studies that it might actually cause collagen disorganization in horses.

Originally, many veterinarians thought using ultrasound to guide injection of PSGAG or hyaluronic acid (HA) into the affected area of the tendon/ligament (and/or intralesional therapy) meant faster healing and fewer adhesions, but researchers have found little evidence of efficacy, so that means that this way of treating tendon injury in horse would not really work.

Intralesional corticosteroids and beta-aminopropionitrile fumarate (BAPN) have also fallen out of favour due to steroid-caused mineralization and tissue necrosis, BAPN withdrawal from the market, and lack of BAPN efficacy in trials.

3. Surgical correction

Certain injuries require surgical correction, which can include tendon splitting. In recent years, veterinarians have advocated this method only in acute cases involving a hematoma or seroma (fluid accumulation in the tissues that can become bone infection) because it can help decompress the core lesion. Tenoscopy is a tool veterinarian can use to debride small tears contributing to persistent lameness.

Some vets perform surgical desmotomy (ligament division) of the SDFT accessory ligament to release strain, but it’s controversial because it might result in further suspensory ligament injury. Annular ligament desmotomy (that which maintains tendon alignment where the tendons cross a joint) in cases of tendon lesions within the digital flexor tendon sheath can help relieve pressure from the ligaments constricting the flexor tendon sheath at the fetlock.

4. Neurectomy

As a last resort for proximal suspensory desmitis, veterinarians can perform a neurectomy to transect the nerve that innervates the suspensory ligament and alleviate pain. Using this procedure, practitioners have achieved a 79% success rate in returning horses to full work without reinjury.

Advances in Treatment Modalities

Veterinarians have found some forms of complementary therapy helpful in treating horse tendon and ligament injury. Therapeutic ultrasound and low-level laser therapy might improve blood flow and stimulate fibroblast (cell that helps connective tissue form) proliferation, but researchers have yet to prove the approaches’ efficacy in controlled equine trials. In humans, researchers have proven acupuncture effectively treats pain associated with tendinopathy (simply, tendon disease) in patients with chronic Achilles tendinopathy.

Biologics have emerged as the most promising tendon and ligament injury treatment. Historically, none of these modalities has been consistently superior to another for a return to performance without reinjury. Part of the issue seems to be a lack of spontaneous regeneration, or healing, of the tendon or ligament after injury.

5. PRP – Platelet – Rich Plasma

Platelet-rich plasma (PRP), a blood product that contains at least twice the platelet count of normal blood, provides high levels of growth factors for healing. “In a typical healing environment, platelets are the first responders to the scene and are the first to produce a call to action from inflammatory and tissue-forming cells,” says Karen Blake, DVM, Dipl. ACVS, surgeon, and owner of Elite Veterinary Services LLC, in Park City, Utah. Experimental and clinical studies focusing on the ideal PRP treatment regimen are ongoing.

6. Scaffold-Based Therapy

Another novel treatment is scaffold-based therapy, which creates a mini-ecosystem in a wound along with growth factors and all the signals involved in the healing process.

Equine tendond and ligament treatment with stem cell therapy
Equine orthopedic problem treatment with stem cell therapy shows very good results

7. Stem Cell Therapy

Stem cells are undifferentiated cells in the body, which means they can give rise to many different cell types with different functions. Veterinarians can collect autologous or allogeneic mesenchymal stem cells (MSCs) from adult horses and inject them into the patient. As early as in 1961 researchers determined MSCs would develop into tendon cells in the laboratory, and in the 1990s scientists confirmed that the cells regenerated new tendon-like tissue in animals.

Stem cell treatment is currently the best way to treat an overstrain injury of the superficial digital flexor tendon,”

says Roger Smith, MA, VetMB, Ph.D., DEO, Dipl. ECVS, MRCVS, a professor at the University of London’s Royal Veterinary College, adding that treated horses have “approximately half the risk of reinjury compared to horses treated with other techniques.”

Stem Cell Therapy Statistics about Treating Tendon & Ligament Injury in Horses

Researchers have shown that National Hunt racehorses treated with stem cell therapy had an 80% return-to-performance rate as compared to the typical 30% with conventional techniques.

“Stem cells appear to improve healing by increasing collagen production and improving organization of the collagen fibers, allowing the tendon to be more normal in structure at the end of the rehabilitation program,” Blake says. 

If your horse does experience a tendon/ligament injury, work with your vet to identify the issue promptly and take appropriate diagnostic and treatment steps to resolve the problem and avoid reinjury.

If you want to ensure that your animal is receiving the best treatment possible and get back to racing as soon as possible by the use of stem cells, Medrego team will help you.

Our Medrego EquiCell treatment with a high 90% success rate has helped several hundreds of horses, and it is ready to help yours as well. Contact us to get more information!

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